Genetics and Molecular Medicine Terms

A type of virus that has hemagglutinin-neuraminidase proteins in the outer coat and RNA as the genetic material.

A family of DNA repair enzymes whose blockade kills cancer cells that have already lost their other way of mending breaks.

PARP inhibitors block an enzyme that helps repair DNA damage, a strategy especially effective against cancers already missing a separate repair pathway.

An enzyme involved in many functions of the cell, including the repair of DNA damage.

PCR rapidly generates millions of copies of a targeted DNA sequence in a test tube, a core technique behind many infection and genetic tests.

A sterile non-pyrogenic suspension of microspheres of human serum albumin with the stable, high-molecular-weight fluorocarbon gas perflutren, used as a contrast enhancement agent for ultrasound…

An inherited condition pairing dark freckle-like spots on the lips with polyps throughout the gut and a raised lifetime cancer risk.

Phenylketonuria is an inherited disorder that impairs breakdown of the amino acid phenylalanine, which then accumulates and can impair development if untreated.

The first chromosome fault ever tied to a specific cancer, and now the target of drugs that switch off the protein it creates.

A new generation organic platinum analog with an extended spectrum of antineoplastic activity.

An inherited disorder that causes a build-up of phenylalanine (an amino acid) in the blood.

The number of sets of chromosomes in a cell or an organism.

One of a group of cancers that develop from the same type of early cells, and share certain biochemical and genetic features.

A plasmid DNA cancer vaccine encoding the intracellular domain (ICD) of the HER-2/neu proto-oncogene.

A type of enzyme involved in many functions of the cell, including the repair of DNA damage.

A substance that blocks an enzyme involved in many functions of the cell, including the repair of DNA damage.

A synthetic RNA that imitates a virus, used to rouse the immune system rather than to attack anything directly.

A stretch of synthetic double-stranded RNA carrying no message at all, built solely to look to the body like a virus.

A synthetic complex of carboxymethylcellulose, polyinosinic-polycytidylic acid, and poly-L-lysine double-stranded RNA.

An enzyme involved in many functions of the cell, including the repair of DNA damage.