MedicalTerminology DB

Meaning of PARP-1: An enzyme involved in many functions of the cell, including the repair of DNA damage.

Definition of PARP-1

An enzyme involved in many functions of the cell, including the repair of DNA damage. DNA damage may be caused by normal cell actions, UV light, some anticancer drugs, and radiation used to treat cancer. Inhibitors of PARP-1 are being studied in the treatment of cancer. Also called poly(ADP-ribose) polymerase-1.

For learning, not diagnosis. This glossary provides general educational information and is not a substitute for advice from a qualified healthcare professional. If you may be experiencing a medical emergency, contact local emergency services.