MedicalTerminology DB
General Medical Terms Genetics & Molecular Medicine

poly (ADP-ribose) polymerase inhibitor

Meaning of poly (ADP-ribose) polymerase inhibitor: A substance that blocks an enzyme involved in many functions of the cell, including the repair of DNA damage.

Definition of poly (ADP-ribose) polymerase inhibitor

A substance that blocks an enzyme involved in many functions of the cell, including the repair of DNA damage. DNA damage may be caused by normal cell actions, UV light, some anticancer drugs, and radiation used to treat cancer. It may cause cancer cells to die. It is a type of targeted therapy. Also called PARP inhibitor.

Written and maintained by James Murray Last updated July 21, 2026 Educational reference, not medical advice. Read the limitations.

For learning, not diagnosis. This glossary provides general educational information and is not a substitute for advice from a qualified healthcare professional. If you may be experiencing a medical emergency, contact local emergency services.