Genetics & Molecular Medicine terms

One of a group of cancers that develop from the same type of early cells, and share certain biochemical and genetic features.

A genetically-engineered protein formed by the fusion of prostatic acid phosphatase (PAP) and sargramostim (GM-CSF).

An orally bioavailable second generation proteasome inhibitor (PI) with potential antineoplastic activity.

A gene involved in normal cell growth.

An autologous dendritic cell vaccine with potential immunostimulatory activity.

A tryptamine alkaloid, isolated from various genera of fungi including the genus Psilocybe, with hallucinogenic, anxiolytic, and psychoactive activities.

A cancer vaccine containing plasmid DNA encoding human prostatic acid phosphatase (PAP) (pTVG-HP) with potential immunostimulatory and antineoplastic activities.

One of two chemical compounds that cells use to make the building blocks of DNA and RNA.

A cancer vaccine containing xenogenic DNA from rhesus macaque (Macaca mulatta) that encodes prostate specific antigen (PSA) with potential immunostimulating and antineoplastic activities.

One of two chemical compounds that cells use to make the building blocks of DNA and RNA.

An anticancer drug that stops tumor cells from growing by blocking the ability of cells to make DNA.

A family of genes that may cause cancer when they are mutated (changed).

A short piece of the ras protein, which is made by the ras gene.

In genetics, describes DNA, proteins, cells, or organisms that are made by combining genetic material from two different sources.

RNA from a virus that is used to insert genetic material into cells.

In biology, the process in cells by which an enzyme makes a copy of DNA from RNA.

An antiviral gene that is being studied in the treatment of cancer in patients who have HIV, the virus that causes AIDS.

A family of anticancer drugs that interfere with the growth of tumor cells by blocking the formation of deoxyribonucleotides (building blocks of DNA).

One of two types of nucleic acid made by cells.

A rare inherited disorder that affects the skin and many other parts of the body, including the bones, eyes, nose, hair, nails, teeth, testes, and ovaries.