picoplatin
Meaning of picoplatin: A new generation organic platinum analog with an extended spectrum of antineoplastic activity.
Definition of picoplatin
A new generation organic platinum analog with an extended spectrum of antineoplastic activity. Designed to overcome platinum drug resistance, picoplatin alkylates DNA, forming both inter- and intra-strand cross-linkages, resulting in inhibition of DNA replication and transcription, and the induction of apoptosis.