Genetics & Molecular Medicine terms
Inherited variation, genomics, molecular markers, and targeted molecular care. Browse definitions and meanings below.
Terms in this topic
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A new generation organic platinum analog with an extended spectrum of antineoplastic activity.
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A genetic disorder in which polyps form in the intestine and dark spots appear on the mouth and fingers.
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An inherited disorder that causes a build-up of phenylalanine (an amino acid) in the blood.
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The number of sets of chromosomes in a cell or an organism.
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One of a group of cancers that develop from the same type of early cells, and share certain biochemical and genetic features.
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A plasmid DNA cancer vaccine encoding the intracellular domain (ICD) of the HER-2/neu proto-oncogene.
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A cancer vaccine consisting of the DNA plasmid pNGVL4a-A encoding calreticulin (CRT) linked to a detox form of human papillomavirus (HPV) type 16 E7 antigen, with potential immunomodulating and…
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An antigen-specific DNA cancer vaccine consisting of the coding sequences of a signal peptide (pNGVL4a-Sig), a detox form of the human papillomavirus type 16 (HPV-16) antigen E7, and the heat shock…
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A type of enzyme involved in many functions of the cell, including the repair of DNA damage.
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A substance that blocks an enzyme involved in many functions of the cell, including the repair of DNA damage.
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A synthetic polyadenylic-polyuridylic acid double-stranded RNA.
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A synthetic polyinosinic-polycytidylic acid double-stranded RNA.
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A synthetic complex of carboxymethylcellulose, polyinosinic-polycytidylic acid, and poly-L-lysine double-stranded RNA.
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An enzyme involved in many functions of the cell, including the repair of DNA damage.
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A second generation polyamine analogue, synthesized through the restriction of molecular conformations of parent polyamine compounds, with potential antineoplastic activity.
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A laboratory method used to make many copies of a specific DNA sequence.
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A common change in the genetic code in DNA.
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A study of a group of individuals taken from the general population who share a common characteristic, such as age, sex, or health condition.
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A broad-spectrum, second generation, triazole compound with antifungal activity.
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A replication-defective (ICP4-deleted) herpes simplex virus type 1 (HSV-1) viral vector expressing the human preproenkephalin A (PPE) gene with potential antinociceptive activity.