topoisomerase inhibitor
1 Definition of topoisomerase inhibitor
Meaning of topoisomerase inhibitor: A substance that blocks topoisomerases (enzymes that break and rejoin DNA strands and are needed for cells to divide and grow).
A substance that blocks topoisomerases (enzymes that break and rejoin DNA strands and are needed for cells to divide and grow). Blocking these enzymes may kill cancer cells. Certain topoisomerase inhibitors are being studied in the treatment of cancer.