An IgG murine monoclonal antibody directed against the ganglioside GD3 glycolipid, located in the cell membranes of some tumor cells. Monoclonal antibody R24 … [Read more...]
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live-attenuated Listeria encoding human mesothelin vaccine CRS-207
A recombinant Listeria-based cancer vaccine containing a live-attenuated strain of the facultative intracellular bacterium Listeria monocytogenes (Lm) … [Read more...]
ixabepilone
An orally bioavailable semisynthetic analogue of epothilone B with antineoplastic activity. Ixabepilone binds to tubulin and promotes tubulin polymerization … [Read more...]
iodine I 123 iodobenzamide
A radiopharmaceutical containing the dopamine D2/D3 receptor agonist iodobenzamide (IBZM) labeled with the radionuclide iodine I 123 with dopamine … [Read more...]
IMP321
A T-cell immunostimulatory factor derived from the soluble form of lymphocyte-activation gene 3 (LAG-3) protein with potential antineoplastic activity. Upon … [Read more...]
ICE regimen
A chemotherapy regimen consisting of ifosfamide, carboplatin and etoposide used in the treatment of relapsed and refractory non-Hodgkin and Hodgkin lymphomas. … [Read more...]
reporting delay
The time elapsed before a diagnosed cancer case is reported to the NCI. Currently, the NCI allows a standard delay of 22 months between the end of the diagnosis … [Read more...]
Hsp90 inhibitor XL888
An orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor XL888 … [Read more...]
hepsulfam
A bisulfamic ester which is similar in structure to busulfan and belongs to the family of drugs known as alkylsulfonate alkylating agents. Hepsulfam forms … [Read more...]
HDAC inhibitor SB939
An orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. HDAC inhibitor SB939 inhibits HDACs, which … [Read more...]