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diazoxide

A benzothiadiazine derivate with antihypertensive and hyperglycemic activities. Diazoxide increases membrane permeability to potassium ions in vascular smooth … [Read more...]

Dimericine

A lotion being studied in the treatment of skin cancer and a skin condition called xeroderma pigmentosum. It has an enzyme contained in very tiny, fat-like … [Read more...]

D-cycloserine

An analogue of the amino acid D-alanine with broad-spectrum antibiotic and glycinergic activities. D-cycloserine interferes with bacterial cell wall synthesis … [Read more...]

DC-OVA vaccine

An autologous, multivalent dendritic cell vaccine targeting ovarian cancer with potential immunostimulating and antineoplastic activities. DC-OVA vaccine is … [Read more...]

DEC-205 / NY-ESO-1 fusion protein CDX-1401

A fusion protein consisting of a fully human monoclonal antibody directed against the endocytic dendritic cell (DC) receptor, DEC-205, linked to the … [Read more...]

coxsackievirus A21

A naturally occurring enterovirus with potential antitumor activity. Upon intratumoral administration, coxsackievirus A21 targets and binds to intracellular … [Read more...]

CXCR4 antagonist TG-0054

An orally bioavailable inhibitor of CXC chemokine receptor 4 (CXCR4) with receptor binding and hematopoietic stem cell-mobilization activities. CXCR4 inhibitor … [Read more...]

CMVpp65-A*0201 peptide vaccine

A peptide-based cancer vaccine containing a mutated form of the HLA-A*0201-restricted cytomegaloviral epitope CMVpp65(495-503) with potential immunostimulatory … [Read more...]

3,4-methylenedioxymethamphetamine

A ring-substituted amphetamine derivative, structurally related to the hallucinogen mescaline, with entactogenic, neurotoxic, and motor-stimulatory activities. … [Read more...]

autologous Ad-CD154-transduced CLL B cells

An autologous tumor cell vaccine containing chronic lymphocytic leukemia (CLL) B cells transduced with an adenoviral vector carrying chimeric CD154 (ad-CD154) … [Read more...]