A fully human IgG1 monoclonal antibody directed against human vascular endothelial growth factor receptor 1 (VEGFR-1/FLT-1) with potential antiangiogenesis and … [Read more...]
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Akt inhibitor SR13668
An orally bioavailable indole-3-carbinol (I3C) analogue inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic … [Read more...]
K-ras gene
A gene that may cause cancer when it is mutated (changed). The K-ras gene makes the KRAS protein, which is involved in cell signaling pathways, cell growth, and … [Read more...]
H-ras gene
A gene that may cause cancer when it is mutated (changed). The H-ras gene makes the HRAS protein, which is involved in cell signaling pathways, cell growth, and … [Read more...]
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matuzumab
A humanized monoclonal antibody with antineoplastic activity. Matuzumab binds the epidermal growth factor receptor (EGFR) with highaffinity, competitively … [Read more...]