A synthetic imidazoquinoline with antineoplastic activity. Acodazole intercalates into DNA, resulting in disruption of DNA replication. Use of this agent has … [Read more...]
Search Results for: sign
Hsp90 inhibitor AT13387
A synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor AT13387 … [Read more...]
HLA-A*0201-restricted URLC10-VEGFR1-VEGFR2 multipeptide vaccine
A cancer vaccine containing three HLA-A*2402-restricted peptide epitopes with potential immunostimulatory, antiangiogenic, and antitumor activities. Vaccine … [Read more...]
E7080
A synthetic, orally available inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR/FLK-1) tyrosine kinase with potential … [Read more...]
BRAF(V600E) kinase inhibitor RO5185426
An orally bioavailable, ATP-competitive, small-molecule inhibitor of BRAF(V600E) kinase with potential antineoplastic activity. BRAF(V600E) kinase inhibitor … [Read more...]
autologous anti-PSMA gene-modified T-cells
Autologous prostate specific membrane antigen (PSMA) gene-modified T lymphocytes with potential antineoplastic activity. Human autologous T-lymphocytes are … [Read more...]
anti-HER3 monoclonal antibody U3-1287
A fully human monoclonal antibody directed against the membrane-bound receptor HER3 (ERBB3) with potential antineoplastic activity. Anti-HER3 monoclonal … [Read more...]
anti-VEGFR-1 monoclonal antibody IMC-18F1
A fully human IgG1 monoclonal antibody directed against human vascular endothelial growth factor receptor 1 (VEGFR-1/FLT-1) with potential antiangiogenesis and … [Read more...]
Akt inhibitor SR13668
An orally bioavailable indole-3-carbinol (I3C) analogue inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic … [Read more...]
K-ras gene
A gene that may cause cancer when it is mutated (changed). The K-ras gene makes the KRAS protein, which is involved in cell signaling pathways, cell growth, and … [Read more...]