An orally bioavailable small molecule, targeting the class I phosphatidylinositol 3 kinase (PI3K) family of lipid kinases, with potential antineoplastic … [Read more...]
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zoledronic acid
A synthetic imidazole bisphosphonate analog of pyrophosphate with anti-bone-resorption activity. A third-generation bisphosphonate, zoledronic acid binds to … [Read more...]
autologous PBTL CD19CAR-28 zeta
A preparation of autologous peripheral blood T-lymphocytes (PBTL) that have been genetically modified to express the chimeric antigen receptor (CAR) … [Read more...]
allogeneic melanoma vaccine AGI-101H
A cancer vaccine derived from two gentically modified human melanoma cell lines with potential antineoplastic activity. Allogeneic melanoma vaccine AGI-101H … [Read more...]
PARP inhibitor CEP-9722
A small-molecule prodrug of CEP-8983, a novel 4-methoxy-carbazole inhibitor of the nuclear enzymes poly(ADP-ribose) polymerase (PARP) 1 and 2, with potential … [Read more...]
Hsp90 inhibitor MPC-3100
An orally bioavailable, synthetic, second-generation small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 … [Read more...]
enteric-coated zoledronic acid tablet MER-101
An oral tablet formulation containing zoledronic acid combined with a proprietary absorption enhancer for improved zoledronic acid gastrointestinal absorption … [Read more...]
ARRY-334543
An orally bioavailable inhibitor of the epidermal growth factor receptor family with potential antineoplastic activity. ARRY-334543 selectively and reversibly … [Read more...]
anti-AGS-16 monoclonal antibody AGS-16M18
A humanized monoclonal antibody directed against the activator of g-proteins signaling (AGS) cell surface protein AGS-16 with potential antineoplastic activity. … [Read more...]
JAK1/2 inhibitor CYT387
An orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with potential antineoplastic activity. JAK1/2 inhibitor CYT387 competes with … [Read more...]