A pyrrolotriazine-based compound and a pan inhibitor of receptor tyrosine kinases with potential antineoplastic activity. Pan HER/VEGFR2 receptor tyrosine … [Read more...]
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minocycline hydrochloride
The hydrochloride salt of minocycline, a broad spectrum long-acting derivative of the antibiotic tetracycline, with antibacterial and anti-inflammatory … [Read more...]
plicamycin
An antibiotic isolated from the bacterium Streptomyces plicatus with antineoplastic activity. Plicamycin, also known as mithramycin, binds to the minor groove … [Read more...]
naltrexone hydrochloride
The hydrochloride salt of naltrexone, a noroxymorphone derivative with competitive opioid antagonistic activity. Naltrexone and its metabolite 6-beta-naltrexol … [Read more...]
monoclonal antibody HuHMFG1
A humanized monoclonal antibody directed against MUC1, a mucin glycoprotein overexpressed in breast and other carcinomas. Monoclonal antibody HuHMFG1 … [Read more...]
metformin hydrochloride
The hydrochloride salt of the biguanide metformin with antihyperglycemic activity. Metformin decreases hepatic gluconeogenesis and intestinal absorption of … [Read more...]
MEK inhibitor ARRY-438162
An orally active small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity. MEK inhibitor ARRY-438162, noncompetitive with ATP, … [Read more...]
monoclonal antibody HuAFP31
A humanized monoclonal antibody directed against alpha fetoprotein with potential antineoplastic activity. Upon administration, monoclonal antibody HuAFP31 (mAb … [Read more...]
Pavatym
(Other name for: papaverine) … [Read more...]
pazopanib hydrochloride
The hydrochloride salt of a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively … [Read more...]