monoclonal antibody HuHMFG1

Definition / meaning of monoclonal antibody HuHMFG1

A humanized monoclonal antibody directed against MUC1, a mucin glycoprotein overexpressed in breast and other carcinomas. Monoclonal antibody HuHMFG1 stimulates antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cells expressing MUC1, resulting in a decrease in tumor burden.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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