metformin hydrochloride

Definition / meaning of metformin hydrochloride

The hydrochloride salt of the biguanide metformin with antihyperglycemic activity. Metformin decreases hepatic gluconeogenesis and intestinal absorption of glucose. This agent also increases the number and/or affinity of insulin receptors on muscle and adipose cells, increasing the sensitivity to insulin at receptor and post-receptor binding sites and increasing glucose uptake peripherally.

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