A 3-cyanoquinoline pan-ErbB tyrosine kinase inhibitor with potential antineoplastic activity. EKB-569 irreversibly binds covalently to epidermal growth factor … [Read more...]
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edotecarin
A synthetic indolocarbazole with antineoplastic activity. Edotecarin inhibits the enzyme topoisomerase I through stabilization of the DNA-enzyme complex and … [Read more...]
benzydamine hydrochloride
An indazole non-steroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic, and anti-edema properties. Unlike other NSAIDs, benzydamine hydrochloride … [Read more...]
bexarotene
A synthetic retinoic acid agent with potential antineoplastic, chemopreventive, teratogenic and embryotoxic properties. Bexarotene selectively binds to and … [Read more...]
DNP-modified autologous renal cell carcinoma tumor cell vaccine
A cancer vaccine consisting of autologous renal cell carcinoma (RCC) tumor cells modified with the hapten 2,4-dinitrophenol (DNP) with potential … [Read more...]
diethyldithiocarbamate
A sulfhydryl-containing carbamate that is the primary in vivo metabolite of disulfiram. Diethyldithiocarbamate chelates zinc, thereby inhibiting … [Read more...]
dihydrotestosterone
The most potent androgen, required for sex development. Dihydrotestosterone is synthesized from testosterone in the prostate gland, testes, hair follicles and … [Read more...]
CXCR4 inhibitor MSX-122
An orally bioavailable inhibitor of CXCR4 with potential antineoplastic and antiviral activities. CXCR4 inhibitor MSX-122 binds to the chemokine receptor … [Read more...]
codeine phosphate
The phosphate salt of codeine, a naturally occurring phenanthrene alkaloid and opioid agonist with analgesic, antidiarrheal and antitussive activities. Codeine … [Read more...]
COPP regimen
A chemotherapy regimen consisting of cyclophosphamide, vincristine (Oncovin), procarbazine and prednisone used for the treatment of Hodgkin and non-Hodgkin … [Read more...]