A synthetic, 20-base antisense oligodeoxynucleotide that hybridizes to c-raf kinase messenger RNA. ISIS 5132 has been shown to specifically suppress Raf-1 … [Read more...]
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iodine I 123
A radioactive isotope of iodine, a nonmetallic element of the halogen group with an atomic mass of 123 and a half-life of 13.2 hours with radioisotopic … [Read more...]
indole-3-carbinol
A naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, a natural compound present in a wide variety of plant food … [Read more...]
IL-2/Lptn gene-modified allogeneic neuroblastoma tumor cell vaccine
A cancer vaccine consisting of allogeneic neuroblastoma tumor cells have been genetically modified to secrete the human cytokine interleukin-2 (IL-2) and the … [Read more...]
IGF-1R antagonist BMS-754807
An orally bioavailable antagonist of human insulin-like growth factor type I receptor (IGF-1R) with potential antineoplastic activity. IGF-1R antagonist … [Read more...]
Annual Report to the Nation
An annual update of cancer death rates, incidence rates (new cases), and trends in the United States. The Centers for Disease Control and Prevention, the … [Read more...]
HSP90 inhibitor HSP990
An orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor Hsp990 binds to and inhibits the … [Read more...]
HLA-A1, A2, B35-restricted survivin peptides / Montanide ISA-51 vaccine
A peptide vaccine comprised of synthetic HLA-A1, -A2 and -B35 restricted survivin epitopes combined with the adjuvant Montanide ISA-51 with potential … [Read more...]
Hedgehog pathway inhibitor IPI-926
An orally bioavailable, cyclopamine-derived inhibitor of the Hedgehog (Hh) pathway with potential antineoplastic activity. Specifically, Hedgehog pathway … [Read more...]
HDAC inhibitor CHR-2845
A hydroxamic acid-derived histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. CHR-2845 inhibits HDAC leading to an accumulation of … [Read more...]