A pentadentate aromatic metallotexaphyrin with photosensitizing properties. Motexafin lutetium preferentially accumulates in tumor cells due to their increased … [Read more...]
Search Results for: Rti
marimastat
An orally-active synthetic hydroxamate with potential antineoplastic activity. Marimastat covalently binds to the zinc(II) ion in the active site of matrix … [Read more...]
pentoxifylline
A methylxanthine derivative with hemorrheologic and immunomodulating properties. Pentoxifylline inhibits phosphodiesterase, resulting in increased levels of … [Read more...]
Melan-A VLP vaccine
A vaccine consisting of the melanocyte differentiation antigen Melan A (also called MART-1) encapsulated in noninfectious virus-like particles (VLP) with … [Read more...]
NY-ESO-B
A tumor-associated antigen belonging to the family of immunogenic testicular proteins that are aberrantly expressed in human cancers in a lineage-nonspecific … [Read more...]
MAGE-A1, Her-2/neu, FBP peptides ovarian cancer vaccine
A cancer vaccine containing multiple synthetic antigen peptides derived from MAGE-A1, Her-2/neu, and folate binding protein (FBP) with potential … [Read more...]
piritrexim
A synthetic antifolate agent with antiparasitic, antipsoriatic and antitumor properties. Piritrexim inhibits the enzyme dihydrofolate reductase enzyme, thereby … [Read more...]
motexafin gadolinium
A synthetic metallotexaphyrin with radiosensitizing and chemosensitizing properties. Motexafin gadolinium accumulates in tumor cells preferentially due to their … [Read more...]
mechlorethamine hydrochloride
The hydrochloride salt of mechlorethamine, a nitrogen mustard and an analogue of sulfur mustard, with antineoplastic and immunosuppressive activities. … [Read more...]
pyrimethamine
A synthetic derivative of ethyl-pyrimidine with potent antimalarial properties. Pyrimethamine is a competitive inhibitor of dihydrofolate reductase (DHFR). … [Read more...]