piritrexim

Meaning of piritrexim: A synthetic antifolate agent with antiparasitic, antipsoriatic and antitumor properties.

Definition of piritrexim

A synthetic antifolate agent with antiparasitic, antipsoriatic and antitumor properties. Piritrexim inhibits the enzyme dihydrofolate reductase enzyme, thereby disrupting folate metabolism and DNA synthesis and cell division.

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