piritrexim
Meaning of piritrexim: A synthetic antifolate agent with antiparasitic, antipsoriatic and antitumor properties.
Definition of piritrexim
A synthetic antifolate agent with antiparasitic, antipsoriatic and antitumor properties. Piritrexim inhibits the enzyme dihydrofolate reductase enzyme, thereby disrupting folate metabolism and DNA synthesis and cell division.