The hydrochloride salt of a third-generation synthetic 9-amino-anthracycline with antineoplastic activity. Amrubicin intercalates into DNA and inhibits the … [Read more...]
Search Results for: RN
pegylated recombinant human arginase I BCT-100
A recombinant human arginase I (liver arginase) covalently attached, via a succinamide propionic acid (SPA) linker, to a polyethylene glycol (PEG) of molecular … [Read more...]
pegylated anti-GFR antibody fragment
A pegylated, cross-linked, humanized divalent-Fab' antibody fragment directed against vascular endothelial growth factor receptor-2 (VEGFR-2) with potential … [Read more...]
N-phosphonacetyl-L-aspartate
A stable transition state analogue for an aspartate transcarbamylase- cartalyzed reaction with antineoplastic activity. N-phosphonacetyl-L-aspartate (PALA) is a … [Read more...]
Attention Deficit Hyperactivity Disorder (ADHD)
A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and … [Read more...]
HLA-A*2402-restricted URLC10-KOC1-VEGFR1-VEGFR2 multipeptide vaccine
A cancer vaccine containing four HLA-A*2402-restricted peptide epitopes with potential immunostimulatory and antitumor activities. Peptide epitopes in this … [Read more...]
6-azauridine
A synthetic triazine analogue of uridine with antimetabolite activity. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted … [Read more...]
anti-EGFRvIII immunotoxin MR1-1
A recombinant immunotoxin consisting of single-chain variable domain fragment antibody directed against the tumor-specific antigen EGFRvIII (MR1scFv) fused to … [Read more...]
GPX-100
An analogue of the anthracycline antineoplastic antibiotic doxorubicin. GPX-100 intercalates DNA and interacts with topoisomerase II, thereby inhibiting DNA … [Read more...]
folate receptor-targeted vinca alkaloid / mitomycin C EC0225
A folate receptor-targeting cytotoxic agent with potential antineoplastic activity. Folate receptor-targeted vinca alkaloid/mitomycin C EC0225 contains two … [Read more...]