A stable transition state analogue for an aspartate transcarbamylase- cartalyzed reaction with antineoplastic activity. N-phosphonacetyl-L-aspartate (PALA) is a … [Read more...]
Search Results for: RN
Attention Deficit Hyperactivity Disorder (ADHD)
A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and … [Read more...]
HLA-A*2402-restricted URLC10-KOC1-VEGFR1-VEGFR2 multipeptide vaccine
A cancer vaccine containing four HLA-A*2402-restricted peptide epitopes with potential immunostimulatory and antitumor activities. Peptide epitopes in this … [Read more...]
6-azauridine
A synthetic triazine analogue of uridine with antimetabolite activity. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted … [Read more...]
anti-EGFRvIII immunotoxin MR1-1
A recombinant immunotoxin consisting of single-chain variable domain fragment antibody directed against the tumor-specific antigen EGFRvIII (MR1scFv) fused to … [Read more...]
GPX-100
An analogue of the anthracycline antineoplastic antibiotic doxorubicin. GPX-100 intercalates DNA and interacts with topoisomerase II, thereby inhibiting DNA … [Read more...]
folate receptor-targeted vinca alkaloid / mitomycin C EC0225
A folate receptor-targeting cytotoxic agent with potential antineoplastic activity. Folate receptor-targeted vinca alkaloid/mitomycin C EC0225 contains two … [Read more...]
floxuridine
A fluorinated pyrimidine monophosphate analogue of 5-fluoro-2'-deoxyuridine-5'-phosphate (FUDR-MP) with antineoplastic activity. As an antimetabolite, … [Read more...]
c-myb antisense oligonucleotide G4460
A 24-base phosphorothiolate antisense oligodeoxynucleotide (ODN) for the proto-oncogene c-myb with potential antineoplastic activity. C-myb antisense … [Read more...]
AVR118
A peptide-nucleic acid immunomodulator with proinflammatory, broad-spectrum antiviral, and potential antineoplastic activities. AVR118 stimulates the peripheral … [Read more...]