The hydrochloride salt of minocycline, a broad spectrum long-acting derivative of the antibiotic tetracycline, with antibacterial and anti-inflammatory … [Read more...]
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plicamycin
An antibiotic isolated from the bacterium Streptomyces plicatus with antineoplastic activity. Plicamycin, also known as mithramycin, binds to the minor groove … [Read more...]
naltrexone hydrochloride
The hydrochloride salt of naltrexone, a noroxymorphone derivative with competitive opioid antagonistic activity. Naltrexone and its metabolite 6-beta-naltrexol … [Read more...]
metformin hydrochloride
The hydrochloride salt of the biguanide metformin with antihyperglycemic activity. Metformin decreases hepatic gluconeogenesis and intestinal absorption of … [Read more...]
nilutamide
A synthetic, nonsteroidal agent with antiandrogenic properties. Nilutamide preferentially binds to androgen receptors and blocks androgen receptor activation by … [Read more...]
MEK inhibitor ARRY-438162
An orally active small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity. MEK inhibitor ARRY-438162, noncompetitive with ATP, … [Read more...]
MLN2704
An immunoconjugate that consists of a humanized monoclonal antibody (MLN591), directed against prostate-specific membrane antigen linked to a maytansinoid … [Read more...]
pazopanib hydrochloride
The hydrochloride salt of a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively … [Read more...]
poly AU
A synthetic polyadenylic-polyuridylic acid double-stranded RNA. Poly AU may stimulate the release of cytotoxic cytokines and, by inducing the production of … [Read more...]
nedaplatin
A second-generation cisplatin analogue with antineoplastic activity. Containing a novel ring structure in which glycolate is bound to the platinum by a … [Read more...]