A nitrosourea with antineoplastic activity. Nimustine alkylates and crosslinks DNA, thereby causing DNA fragmentation, inhibition of protein synthesis, and cell … [Read more...]
Search Results for: K C
progenipoietin
A recombinant, chimeric, dual-receptor agonist fusion protein with immunohematopoietic activity. Progenipoietin (ProGP) consists of portions of the ligands for … [Read more...]
MOPP regimen
A chemotherapy regimen consisting of mechlorethamine, vincristine (Oncovin), procarbazine and prednisone, used alone or in combination with radiation therapy … [Read more...]
ONYX-015
An E1B-55kDa-deleted adenovirus that is able to selectively replicate in and lyse TP53-deficient human tumor cells. After tumor cell lysis, released viruses … [Read more...]
povidone-iodine solution
An iodophor solution containing a water-soluble complex of iodine and polyvinylpyrrolidone (PVP) with broad microbicidal activity. Free iodine, slowly … [Read more...]
paclitaxel poliglumex
The agent paclitaxel linked to a biodegradable, water-soluble polyglutamate polymer with antineoplastic properties. The polyglutamate residue increases the … [Read more...]
piperazinedione
A crystalline antibiotic fermentation product isolated from the bacterium Streptomyces griseoluteus with antineoplastic activity. Piperazinedione alkylates DNA … [Read more...]
polyvalent antigen-KLH conjugate vaccine
A multivalent cancer vaccine comprised of the five tumor-associated antigens (TAAs) globo H, GM2 ganglioside, Tn-MUC1, TF, and sTn conjugated with the … [Read more...]
papaverine
An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. As a direct-acting smooth muscle relaxant, papaverine is not closely … [Read more...]
naloxone hydrochloride
The hydrochloride salt of naloxone, a thebaine derivate with opioid antagonist activity. Naloxone binds to opioid receptors in the CNS in a competitive manner, … [Read more...]