paclitaxel poliglumex

Meaning of paclitaxel poliglumex: The agent paclitaxel linked to a biodegradable, water-soluble polyglutamate polymer with antineoplastic properties.

Definition of paclitaxel poliglumex

The agent paclitaxel linked to a biodegradable, water-soluble polyglutamate polymer with antineoplastic properties. The polyglutamate residue increases the water solubility of paclitaxel and allows delivery of higher doses than those achievable with paclitaxel alone. Paclitaxel promotes microtubule assembly and prevents microtubule depolymerization, thus interfering with normal mitosis.

For learning, not diagnosis. This glossary provides general educational information and is not a substitute for advice from a qualified healthcare professional. If you may be experiencing a medical emergency, contact local emergency services.