monoclonal antibody HeFi-1

Definition / meaning of monoclonal antibody HeFi-1

A murine monoclonal antibody with potential antineoplastic activity. Monoclonal antibody HeFi-1 binds to CD30, a cell surface antigen found on mitogen-activated B-cells and T-cells, and Reed-Sternberg cells. Monoclonal antibody HeFi-1 has been shown to arrest tumor growth and prevent metastasis in animal models.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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