MedicalTerminology DB
General Medical Terms Cancer & Oncology

malignant fibrous histiocytoma

Meaning of malignant fibrous histiocytoma: A soft tissue sarcoma that usually occurs in the limbs, most commonly the legs, and may also occur in the abdomen.

Definition of malignant fibrous histiocytoma

A soft tissue sarcoma that usually occurs in the limbs, most commonly the legs, and may also occur in the abdomen. Also called malignant fibrous cytoma.

Written and maintained by James Murray Last updated July 21, 2026 Educational reference, not medical advice. Read the limitations.

For learning, not diagnosis. This glossary provides general educational information and is not a substitute for advice from a qualified healthcare professional. If you may be experiencing a medical emergency, contact local emergency services.