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mouse prostate-specific membrane antigen plasmid DNA vaccine

Definition / meaning of mouse prostate-specific membrane antigen plasmid DNA vaccine

A vaccine consisting of a plasmid DNA encoding the murine prostate-specific membrane antigen (PSMA). Upon administration, expressed PSMA may stimulate a cytotoxic T cell response against tumor cells that express PSMA, resulting in tumor cell lysis.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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