monoclonal gammopathy of undetermined significance

Definition / meaning of monoclonal gammopathy of undetermined significance

A benign condition in which there is a higher-than-normal level of a protein called M protein in the blood. Patients with monoclonal gammopathy of undetermined significance are at an increased risk of developing cancer. Also called MGUS.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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