monoclonal antibody R24

Definition / meaning of monoclonal antibody R24

An IgG murine monoclonal antibody directed against the ganglioside GD3 glycolipid, located in the cell membranes of some tumor cells. Monoclonal antibody R24 binds to GD3-positive cells, thereby initiating antibody-dependent cytotoxicity against GD3-positive cells.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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