monoclonal antibody Mik-beta-1

Definition / meaning of monoclonal antibody Mik-beta-1

A murine monoclonal antibody directed against the beta subunit of the interleukin-2 receptor (IL-2R), expressed on resting T-lymphocytes, natural killer (NK) cells, and some leukemic cell types. Monoclonal antibody Mik-beta-1 prevents the binding of IL-2 to IL-2R beta, thereby inhibiting the IL-2-mediated proliferation and activation of T-cells.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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