monoclonal antibody MDX-060

Definition / meaning of monoclonal antibody MDX-060

A monoclonal antibody with potential antineoplastic activity. MDX-060 is a fully humanized antibody that targets CD30, a member of the tumor necrosis factor receptor superfamily found on activated lymphocytes. CD30 is over-expressed in various lymphoproliferative disorders, Hodgkin’s disease and other lymphomas, and other cancers.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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