monoclonal antibody Hu3S193

Definition / meaning of monoclonal antibody Hu3S193

A humanized monoclonal antibody directed against the Lewis Y antigen, a tumor-associated epithelial antigen, with potential antineoplastic activity. Following binding, monoclonal antibody Hu3S193 triggers an antibody-dependent cell-mediated cytotoxicity in cells expressing Lewis Y antigen.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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