monoclonal antibody G250

Definition / meaning of monoclonal antibody G250

A chimeric monoclonal antibody directed against G250, a cell surface antigen found in the majority of renal cell carcinomas. Following binding, monoclonal antibody G250 (mAb G250) may be internalized by G250 antigen-expressing renal carcinoma cells; mAb G250 may be useful as a carrier for radioisotopes and other antineoplastic therapeutic agents.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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