monoclonal antibody E2.3

Definition / meaning of monoclonal antibody E2.3

A murine IgG1 monoclonal antibody directed against the human transferrin (Tf) receptor. Monoclonal antibody E2.3 binds to the Tf receptor, blocking the binding of transferrin to the receptor and resulting in decreased tumor cell growth.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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