monoclonal antibody A27.15

Definition / meaning of monoclonal antibody A27.15

A murine IgG1 monoclonal antibody directed against the human transferrin (Tf) receptor. Monoclonal antibody A27.15 binds to the Tf receptor, blocking the binding of transferrin to the receptor and resulting in decreased tumor cell growth.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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