monoclonal antibody 11D10 anti-idiotype vaccine

Definition / meaning of monoclonal antibody 11D10 anti-idiotype vaccine

A vaccine consisting of a monoclonal antibody (MoAB) directed against an idiotype that mimics a human milk fat globule (HMFG) membrane epitope. Vaccination with monoclonal antibody 11D10 anti-idiotype vaccine induces anti-anti-idiotype antibodies (Ab3) that may react with breast cancer cell lines expressing the HMFG membrane epitope.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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