mitosis-angiogenesis inhibitor R1530

Definition / meaning of mitosis-angiogenesis inhibitor R1530

A pyrazolobenzodiazepine small molecule with potential antiangiogenesis and antineoplastic activities. Mitosis-angiogenesis inhibitor (MAI) R1530 inhibits multiple receptor tyrosine kinases involved in angiogenesis, such as vascular endothelial growth factor receptor (VEGFR)-1, -2, -3, platelet-derived growth factor receptor (PDGFR) beta

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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