methylmercaptopurine riboside

Definition / meaning of methylmercaptopurine riboside

A purine derivative with antineoplastic and anti-angiogenic properties. 6-methylmercaptopurine riboside (6-MMPR) inhibits amidophosphoribosyltransferase, the first committed step in de novo purine synthesis, and inhibits fibroblast growth factor-2 (FGF2)-induced cell proliferation.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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