MART-1 antigen

Definition / meaning of MART-1 antigen

A tumor-associated melanocytic differentiation antigen. Vaccination with MART-1 antigen may stimulate a host cytotoxic T-cell response against tumor cells expressing the melanocytic differentiation antigen, resulting in tumor cell lysis.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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