Definition / meaning of HGS-ETR1

A substance being studied in the treatment of some types of cancer. It binds to a protein called TRAIL R1 on the surface of some tumor cells. This may kill the tumor cells. HGS-ETR1 is a type of monoclonal antibody. Also called anti-TRAIL R1-mAb and mapatumumab.

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The Web site of the National Cancer Institute (http://www.cancer.gov/)

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