HDAC

Definition / meaning of HDAC

An enzyme that removes a small molecule called an acetyl group from histones (proteins found in chromosomes). This changes the way the histones bind to DNA and may affect its activity. HDAC inhibitors are being studied in the treatment of cancer. Also called histone deacetylase.

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Find More About 'HDAC'

Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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