A substance being studied in the treatment of cancer. It is a type of topoisomerase I inhibitor. Also called edotecarin. … [Read more...]

J-pouch coloanal anastomosis

A surgical procedure in which the colon is attached to the anus after the rectum has been removed. A 2-4 inch section of the colon is formed into a J-shaped … [Read more...]

JAK1/2 inhibitor CYT387

An orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with potential antineoplastic activity. JAK1/2 inhibitor CYT387 competes with … [Read more...]

JAK2 inhibitor TG101348

An orally bioavailable, small-molecule, ATP-competitive inhibitor of Janus-associated kinase 2 (JAK2) with potential antineoplastic activity. JAK2 inhibitor … [Read more...]

Jamshidi needle

A long, hollow needle with a tapered cutting edge on one end and a handle with a place to attach a syringe on the other end. It is used to remove a sample of … [Read more...]


A condition in which the skin and the whites of the eyes become yellow, urine darkens, and the color of stool becomes lighter than normal. Jaundice occurs when … [Read more...]


A substance being studied in the treatment of bladder cancer, lung cancer, and other types of cancer. Also called vinflunine. … [Read more...]


An abbreviation for a chemotherapy combination used to treat childhood ovarian and testicular germ cell cancers that have spread. It includes the drugs … [Read more...]

JEB regimen

A chemotherapy regimen consisting of carboplatin (JM8), etoposide and bleomycin used for the treatment of childhood extracranial germ cell tumors. (NCI … [Read more...]


(Other name for: cabazitaxel) … [Read more...]