A substance that blocks signals passed from one molecule to another inside a cell. Blocking these signals can affect many functions of the cell, including cell … [Read more...]
Search Results for: sign
signaling pathway
Describes a group of molecules in a cell that work together to control one or more cell functions, such as cell division or cell death. After the first molecule … [Read more...]
signal transduction
The process by which a cell responds to substances in its environment. The binding of a substance to a molecule on the surface of a cell causes signals to be … [Read more...]
Tasigna
A drug used to treat certain types of chronic myelogenous leukemia (CML). It is used in patients who have not gotten better after treatment with other … [Read more...]
statistically significant
Describes a mathematical measure of difference between groups. The difference is said to be statistically significant if it is greater than what might be … [Read more...]
PI3K inhibitor BGT226
A phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BGT226 specifically inhibits PIK3 in the PI3K/AKT kinase … [Read more...]
parathyroid hormone-related protein (1-36)
A recombinant form of a mature, N-terminal secretory peptide derived from a parathyroid hormone-related protein (PTHrP) preprohormone through posttranslational … [Read more...]
PI3K inhibitor PX-866
A small-molecule wortmannin analogue inhibitor of the alpha, gamma, and delta isoforms of phosphoinositide 3-kinase (PI3K) with potential antineoplastic … [Read more...]
nafoxidine hydrochloride
The hydrochloride salt of the partial estrogen antagonist nafoxidine. Nafoxidine competes with endogenous estrogen for binding to specific estrogen receptors. … [Read more...]
perifosine
An orally active alkyl-phosphocholine compound with potential antineoplastic activity. Targeting cellular membranes, perifosine modulates membrane … [Read more...]