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anti-EGFRvIII vaccine CDX-110

A cancer vaccine consisting of a human epidermal growth factor receptor variant III (EGFRvIIi)-specific peptide conjugated to the non-specific immunomodulator … [Read more...]

aminopterin

A synthetic derivative of pterins with antineoplastic and immunosuppressive properties. As a folate analogue, aminopterin competes for the folate binding site … [Read more...]

amphotericin B deoxycholate

The deoxycholate salt of amphotericin B, a polyene antifungal antibiotic produced by Streptomyces nodosus, with antifungal activity. Amphotericin B binds to … [Read more...]

allogeneic GM-CSF-secreting breast cancer vaccine

An allogenic vaccine consisting of irradiated breast cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene. Upon … [Read more...]

AC regimen

A chemotherapy regimen consisting of doxorubicin hydrochloride (Adriamycin) and cyclophosphamide used in the adjuvant setting for the primary treatment of … [Read more...]

acadesine

A 5-aminoimidazole-4-carboxamide (AICA) riboside, a purine nucleoside analog, and a nucleotide biosynthesis precursor with B cell pro-apoptotic activity. … [Read more...]

adefovir dipivoxil

An acyclic nucleotide adenine analogue with potent antiviral activity. Adefovir is activated in vivo to a diphosphate metabolite which is incorporated into … [Read more...]

lutetium Lu 177-DOTA-edotreotide

A radioconjugate consisting of the octreotide derivative edotreotide (Tyr3-octreotide or TOC) labeled with lutetium Lu 177 with receptor ligand, beta-emitting … [Read more...]

lonafarnib

A synthetic tricyclic derivative of carboxamide with antineoplastic properties. Lonarfanib binds to and inhibits farnesyl transferase, an enzyme involved in … [Read more...]

licorice root extract

An herbal extract derived from the root of the plant Glycyrrhiza glabra with potential anti-inflammatory, antioxidant, and antineoplastic activities. Licorice … [Read more...]