A covalent conjugate of recombinant interferon alpha, subtype 2b, and polyethylene glycol (PEG), used as an antiviral and antineoplastic agent. The biological … [Read more...]
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NA17-A antigen
A specific melanoma antigen protein derived from a patient (NA17) with cutaneous melanoma metastases. When administered in a vaccine formulation, NA17-A … [Read more...]
menatetrenone
A menaquinone compound and form of vitamin K2 with potential antineoplastic activity. Menatetrenone may act by modulating the signalling of certain tyrosine … [Read more...]
monoclonal antibody KW-2871
A low-fucose, human-mouse chimeric IgG1 monoclonal antibody directed against the ganglioside GD3, a surface antigen expressed on many malignant melanoma cells, … [Read more...]
mesna
A sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents. Mesna is converted to a … [Read more...]
PARP inhibitor MK4827
An inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. PARP Inhibitor MK4827 inhibits PARP activity, enhancing the … [Read more...]
pladienolide derivative E7107
A synthetic urethane derivative of pladienolide D with potential antineoplastic activity. Pladienolide derivative E7107 is generated from the 12-membered … [Read more...]
p53 activator APR-246
A quinuclidinone derivative that targets the Wrap53 gene with potential antineoplastic activity. p53 activator APR-246 binds to and activates transcription of … [Read more...]
oncolytic measles virus encoding thyroidal sodium iodide symporter
An attenuated oncolytic Edmonston (Ed) strain of measles virus encoding the human thyroidal sodium iodide symporter (MV-NIS) with potential gene expression and … [Read more...]
MUC-1 peptide vaccine
A cancer vaccine comprised of a synthetic peptide derived from the mucin 1 (MUC-1) antigen with potential antineoplastic activity. Upon administration, MUC-1 … [Read more...]