A cancer vaccine consisting of a proprietary, recombinant modified vaccinia Ankara (MVA) viral vector encoding an epitope of human epidermal growth factor … [Read more...]
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multitargeted tyrosine kinase inhibitor BIBF 1120
An orally bioavailable, indolinone-derived, receptor tyrosine kinase (RTK) inhibitor with potential antiangiogenic and antineoplastic activities. Multitargeted … [Read more...]
microtubulin inhibitor EPC2407
A small molecule tubulin polymerization inhibitor with potential antineoplastic activity. Microtubulin inhibitor EPC2407 binds to the colchicine-binding site on … [Read more...]
pyruvate kinase inhibitor TLN-232
A synthetic cyclic heptapeptide with potential antineoplastic activity. Pyruvate kinase (PK) inhibitor TLN-232 targets pyruvate kinase M2 (M2PK), which may … [Read more...]
pemetrexed disodium
The disodium salt of a synthetic pyrimidine-based antifolate. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the … [Read more...]
OSI-7904L
A liposome-encapsulated formulation of the benzoquinazoline folate analog OSI-7904 with antineoplastic activity. As a thymidylate synthase inhibitor, OSI-7904 … [Read more...]
proteasome inhibitor MLN9708
An orally bioavailable second generation proteasome inhibitor (PI) with potential antineoplastic activity. Proteasome inhibitor MLN9708 inhibits the activity of … [Read more...]
natalizumab
A humanized recombinant IgG4 monoclonal antibody directed against the alpha4 subunit of the integrins alpha4beta1 and alpha4beta7 with immunomodulating, … [Read more...]
monoclonal antibody CAL
A humanized monoclonal antibody directed against parathyroid hormone-related protein (PTH-rP). As a poly-hormone with diverse biological roles, PTH-rP is … [Read more...]
MEK inhibitor AZD6244
An orally bioavailable small molecule with potential antineoplastic activity. MEK inhibitor AZD6244 inhibits mitogen-activated protein kinase kinases (MEK or … [Read more...]