An orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity. MEK inhibitor AS703026 selectively binds to … [Read more...]
Search Results for: K C
perfosfamide
The active metabolite of the nitrogen mustard cyclophosphamide with potent antineoplastic and immunosuppressive properties. Perfosfamide alkylates DNA, thereby … [Read more...]
oral JAK2 inhibitor SB1518
An orally bioavailable inhibitor of Janus kinase 2 (JAK2) and the JAK2 mutant JAK2V617F with potential antineoplastic activity. Oral JAK2 inhibitor SB1518 … [Read more...]
oral picoplatin
An oral preparation of picoplatin, a third generation platinum compound with antineoplastic activity. Designed to overcome platinum drug resistance, picoplatin … [Read more...]
PPE-expressing replication-defective HSV-1 vector NP2
A replication-defective (ICP4-deleted) herpes simplex virus type 1 (HSV-1) viral vector expressing the human preproenkephalin A (PPE) gene with potential … [Read more...]
PM00104
A synthetic tetrahydroisoquinoline alkaloid related to the marine natural compounds Jorumycin and the family of Renieramycins, obtained from molluscs and … [Read more...]
monoclonal antibody A33
A humanized monoclonal antibody directed against the human A33 antigen. Monoclonal antibody A33 recognizes the human A33 antigen, a 43 KDa transmembrane … [Read more...]
macrogol 3350-based oral osmotic laxative
An isotonic solution containing macrogol 3350 and electrolytes with laxative activity. Macrogol 3350-based oral osmotic laxative promotes the retention of … [Read more...]
PVDF / sirolimus topical
A topical formulation consisting of a polyvinylidene fluoride (PVDF) polymer resin containing the macrolide sirolimus (rapamycin), produced by the organism … [Read more...]
MET tyrosine kinase inhibitor PF-04217903
An orally bioavailabe, small-molecule tyrosine kinase inhibitor with potential antineoplastic activity. MET tyrosine kinase inhibitor PF-04217903 selectively … [Read more...]