Search Results for: DM


In medicine, the act of giving a treatment, such as a drug, to a patient. It can also refer to the way it is given, the dose, or how often it is given. … [Read more...]


A substance that is being studied in the treatment of prostate cancer. It belongs to the family of drugs called antibody drug conjugates. Also called MLN2704. … [Read more...]

maytansinoid DM4-conjugated humanized monoclonal antibody huC242

A substance being studied in the treatment of some types of cancer. It is made by linking the monoclonal antibody huC242 to a toxic substance called … [Read more...]

anti-CD3 immunotoxin A-dmDT390-bisFv(UCHT1)

A bivalent recombinant fusion protein immunotoxin derived from the anti-CD3 monoclonal antibody UCHT1 with potential antineoplastic activity. Anti-CD3 … [Read more...]

Food and Drug Administration

Anagency in the U.S. federal government whose mission is toprotect public health by making sure that food, cosmetics,and nutritional supplements are safe to use … [Read more...]


A metallic element that occurs naturally in tiny amounts in air, water, soil, and food. It is a byproduct of zinc refining, and is used to make batteries, … [Read more...]

anti-CD33 monoclonal antibody-DM4 conjugate AVE9633

An immunoconjugate consisting of the humanized monoclonal antibody huMy9-6 conjugated to the cytotoxic maytansinoid DM4 with potential antineoplastic activity. … [Read more...]

HDM2 antagonist JNJ-26854165

An orally bioavailable, small-molecule HDM2 antagonist with potential antineoplastic activity. HDM2 antagonist JNJ-26854165 inhibits the binding of theHDM2 … [Read more...]

anti-integrin monoclonal antibody-DM4 immunoconjugate IMGN388

An immunoconjugate consisting of an anti-integrin monoclonal antibody covalently attached to the maytansinoid DM4, a derivative of the cytotoxic agent … [Read more...]


An immunotoxin of a humanized monoclonal antibody C242 (MoAb HuC242) conjugated with a derivative of cytotoxic agent maytansine, DM4, with potential antitumor … [Read more...]