Search Results for: CANCER TYPES

DEC-205 / NY-ESO-1 fusion protein CDX-1401

A fusion protein consisting of a fully human monoclonal antibody directed against the endocytic dendritic cell (DC) receptor, DEC-205, linked to the … [Read more...]

human papillomavirus 16/18 L1 virus-like particle / AS04 vaccine

A recombinant, bivalent, human papillomavirus (HPV) vaccine, containing virus-like particles for HPV types 16 and 18 linked to the adjuvant ASO4, with potential … [Read more...]

CDK2 / TRKA inhibitor PHA-848125 AC

An orally bioavailable inhibitor of cyclin-dependent kinases (CDKs) and thropomyosin receptor kinase A (TRKA), with potential antineoplastic activity. CDK2/TRKA … [Read more...]

cixutumumab

A fully human IgG1 monoclonal antibody directed against the human insulin-like growth factor-1 receptor (IGF-1R) with potential antineoplastic activity. … [Read more...]

gamma-D-glutamyl-L-tryptophan

An orally bioavailable synthetic peptide containing the amino acids D-glutamine and L-tryptophan connected by a gamma-glutamyl linkage with potential … [Read more...]

CK2 inhibitor CX-4945

An orally bioavailable small-molecule inhibitor of CK2 with potential antineoplastic activity. CK2 inhibitor CX-4945 selectively binds to and inhibits the … [Read more...]

cell cycle checkpoint / DNA repair antagonist IC83

A proprietary agent with potential antineoplastic activity. Cell cycle checkpoint/DNA repair antagonist IC83 IC83 inhibits cell cycle checkpoint/DNA repair … [Read more...]

anti-HGF monoclonal antibody AMG 102

A fully human IgG2 monoclonal antibody directed against the human hepatocyte growth factor (HGF) with potential antineoplastic activity. Anti-HGF monoclonal … [Read more...]

bafetinib

An orally bioavailable 2-phenylaminopyrimidine derivative with potential antineoplastic activity. Bafetinib specifically binds to and inhibits the Bcr/Abl … [Read more...]

dovitinib lactate

The orally bioavailable lactate salt of a benzimidazole-quinolinone compound with potential antineoplastic activity. Dovitinib strongly binds to fibroblast … [Read more...]