A small-molecule inhibitor of the serine-threonine kinase Aurora B with potential antineoplastic activity. Aurora B kinase inhibitor TAK-901 binds to and … [Read more...]
Search Results for: CANCER TYPES
bexarotene
A synthetic retinoic acid agent with potential antineoplastic, chemopreventive, teratogenic and embryotoxic properties. Bexarotene selectively binds to and … [Read more...]
anti-EphA2 monoclonal antibody-MMAF immunoconjugate MEDI-547
An auristatin analogue immunoconjugate directed against Eph receptor A2 (EphA2)-positive cancer cells with potential antineoplastic activity. Anti-EphA2 … [Read more...]
B16alphaGal melanoma vaccine
A whole cell melanoma cancer vaccine with potential immunostimulating and antineoplastic activities. B16alphaGal melanoma vaccine contains three types of human … [Read more...]
indium In 111 monoclonal antibody huPAM4
The humanized monoclonal antibody huPAM4, directed against the pancreatic cancer antigen MUC-1 and radiolabled with the gamma-emitting radioisotope indium I … [Read more...]
EGFR / HER2 tyrosine kinase inhibitor BIBW 2992
An orally bioavailable dual receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. EGFR/HER2 tyrosine kinase inhibitor BIBW 2992 … [Read more...]
hTERT / survivin / melanoma tumor cell-derived mRNA-transfected dendritic cell vaccine
A cancer vaccine containing dendritic cells (DCs) that are transfected with messenger RNA (mRNA) encoding human telomerase reverse transcriptase (hTERT) and … [Read more...]
gold sodium thiomalate
The sodium salt of gold thiomalic acid, an organogold compound with antirheumatic and potential antineoplastic activities. Gold sodium thiomalate (GST) appears … [Read more...]
CHK2 inhibitor LY2603618
An inhibitor of the cell cycle checkpoint kinase 2 (chk2) with potential chemopotentiating activity. Chk2 inhibitor LY2603618 binds to and inhibits the activity … [Read more...]
anti-MET monoclonal antibody MetMAb
A humanized monovalent monoclonal antibody directed against the hepatocyte growth factor receptor (c-Met) with potential antineoplastic activity. Anti-MET … [Read more...]